Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep751 | Pituitary and Neuroendocrinology | ECE2022

Immunohistochemichal expression of ephrin receptor (EPH)-A4, -A5, -B2 and -B5 in pituitary lesions

Papadimitriou Eirini , Kyriakopoulos Georgios , Barkas Konstantinos , Gkalonakis Ioannis , Pantoula Panagiota , Theocharis Stamatios , Kaltsas Gregory , Alexandraki Krystallenia

Introduction: Ephrin receptors (EPHs) compose the largest known subfamily of receptors tyrosine kinases and are bound and interact with EPHs-interacting proteins (Ephrins). They have a role in tumor growth, invasion, angiogenesis and metastasis of several neoplasms. Aim of the study was to investigate the expression of EPH-A4, -A5, -B2 and -B5 in pituitary lesions. Material and Methods: Our study group consisted of 18 patients (9 males with median age 54...